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Cylert

Pemoline (sold as Cylert®) is a medication used to treat attention-deficit hyperactivity disorder (ADHD). Under the Convention on Psychotropic Substances, it is a Schedule IV drug . more...

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Pemoline has some advantages over other stimulants in that it doesn't reduce the appetite or cause dry mouth. However, in some patients Pemoline is suspected of causing liver damage, so regular liver tests are performed are those treated with it. Since receiving FDA aproval in 1975, it has been linked with 21 cases of liver failure, of which 13 resulted in liver replacement or death. In 2005, the FDA withdrew approval for Pemoline due to pressure from certain public advocacy groups. Patient support group the Narcolepsy Network tried to persuade the FDA not to ban it, on the grounds that some patients find all other treatments ineffective or to have dehabilitating side effects. The medication was used by an estimated 10,000 Americans afflicted with narcolepsy.

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Children in Louisiana are being prescribed stimulant medications for attention deficit hyperactivity disorder at four times the rate as children in the
From Drug Cost Management Report, 3/1/03

* Children in Louisiana are being prescribed stimulant medications for attention deficit hyperactivity disorder (ADHD) at four times the rate as children in the District of Columbia. In general, there is higher utilization of stimulants for ADHD in the South and Midwest regions of the U.S., and in higher-income communities, according to a new study. The study was conducted by Express Scripts and published in the journal Pediatrics. ADHD affects approximately 3% to 5% of school-aged children. ADHD therapies are among the most highly prescribed products for school-age children, and include Concerta, Ritalin, Adderall, Dexadrine and Cylert. Express Scripts researcher Emily Cox, Ph.D., theorizes that the factors responsible for the geographic disparities in prescription rates include state laws, anti-Ritalin campaigns, direct-to-consumer advertising, physician practice styles, and the expectations of teachers and parents. For more information visit www.express-scripts.com/other/news_views/ outcomes_research.htm.

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